%0 Journal Article %T Performance Assessment of a Channel Multi-Pinhole Collimator for Myocardial Perfusion Imaging with SPECT: A Monte Carlo Simulation %J Journal of Nuclear Research and Applications %I Nuclear Science and Technology Research Institute (NSTRI) %Z 2783-3402 %A Mohebbi, Z. %A Saeedzadeh, E. %A Mahani, H. %D 2023 %\ 09/01/2023 %V 3 %N 3 %P 18-22 %! Performance Assessment of a Channel Multi-Pinhole Collimator for Myocardial Perfusion Imaging with SPECT: A Monte Carlo Simulation %K SPECT %K Monte Carlo %K GATE %K MPI %K Multi-pinhole %R 10.24200/jon.2023.1066 %X While the conventional parallel-hole collimators are widely used in myocardial perfusion imaging (MPI) with SPECT, they are suboptimal in balancing the existing sensitivity-resolution compromise. Therefore, multi-pinhole collimation has been proposed to address the problem. In the present study, a channel multi-pinhole collimated SPECT scanner is modeled and then simulated using the GATE Monte Carlo simulation. The multi-pinhole collimator comprises eight apertures. The material, diameter, and height of the apertures were assumed to be varying. A comparison with conventional single-pinhole was also conducted. The results show that increasing the hole diameter leads to degraded spatial resolution for the multi-pinhole collimator. Compared to the single-pinhole, the multi-pinhole collimators suffer from projection overlapping and thus deteriorated spatial resolution. The findings confirm that the channel multi-pinhole collimators outperform the single-pinhole apertures by providing much higher sensitivity at the expense of slightly lower spatial resolution and therefore would be the collimator of choice for MPI with SPECT. %U https://jonra.nstri.ir/article_1476_71b1a36aafba22d4c0ce6672f287d2d4.pdf