An International Peer - Reviewed Journal by Nuclear Science & Technology Research Inistitute

Document Type : Research paper


1 Department of Radiation Medical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran

2 Radiation Applications Research School, Nuclear Science and Technology Research Institute, Tehran, Iran


While the conventional parallel-hole collimators are widely used in myocardial perfusion imaging (MPI) with SPECT, they are suboptimal in balancing the existing sensitivity-resolution compromise. Therefore, multi-pinhole collimation has been proposed to address the problem. In the present study, a channel multi-pinhole collimated SPECT scanner is modeled and then simulated using the GATE Monte Carlo simulation. The multi-pinhole collimator comprises eight apertures. The material, diameter, and height of the apertures were assumed to be varying. A comparison with conventional single-pinhole was also conducted. The results show that increasing the hole diameter leads to degraded spatial resolution for the multi-pinhole collimator. Compared to the single-pinhole, the multi-pinhole collimators suffer from projection overlapping and thus deteriorated spatial resolution. The findings confirm that the channel multi-pinhole collimators outperform the single-pinhole apertures by providing much higher sensitivity at the expense of slightly lower spatial resolution and therefore would be the collimator of choice for MPI with SPECT.


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