An International Double-Blind, Peer-Review Journal by NSTRI

Document Type : Research paper


1 Department of Radiation Medical Engineering, Science and Research Branch, Islamic Azad University, B. O. Box 14515-775, Tehran, Iran

2 Radiation Applications Research School, Nuclear Science and Technology Research Institute, B. O. Box 14395-836, Tehran, Iran


While the conventional parallel-hole collimators are widely used in myocardial perfusion imaging (MPI) with SPECT, they are suboptimal in balancing the existing sensitivity-resolution compromise. Therefore, multi-pinhole collimation has been proposed to address the problem. In the present study, a channel multi-pinhole collimated SPECT scanner is modeled and then simulated using the GATE Monte Carlo simulation. The multi-pinhole collimator comprises eight apertures. The material, diameter, and height of the apertures were assumed to be varying. A comparison with conventional single-pinhole was also conducted. The results show that increasing the hole diameter leads to degraded spatial resolution for the multi-pinhole collimator. Compared to the single-pinhole, the multi-pinhole collimators suffer from projection overlapping and thus deteriorated spatial resolution. The findings confirm that the channel multi-pinhole collimators outperform the single-pinhole apertures by providing much higher sensitivity at the expense of slightly lower spatial resolution and therefore would be the collimator of choice for MPI with SPECT.


Main Subjects

  1. 1. World Health Organization (WHO),

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