Document Type : Research paper
Authors
1 Central Iran Research Complex, Iran Radiation Application Development Company, Atomic Energy Organization of Iran, Tehran, Iran.
2 Nuclear Science and Technology Research Institute
Abstract
In the present work, hemostatic powder based on starch (St) biopolymer was synthesized using a new and innovative production method with the help of electron beam irradiation (EBI). Compared to common chemical methods, the Irradiation methods have advantages such as high production speed (suitable for industrial scale production), no use of common chemicals in polymerization processes (such as initiators or crosslinkers), sterilization and production at the same time, no waste generation and performing the reaction at room temperature. In the first stage, by using and introducing a new method (chlorination and amination of starch and subsequent grafting of plant polyphenols on starch), crosslinking reactions prevailed over chain breaking reactions (under high-energy electron beam irradiation). The chemical and physical structure of the product was studied by FTIR, SEM, EDX, XRD, TGA. The effect of electron beam irradiation dose on swelling, gel percentage and mechanical properties of hemostat product was studied. Considering the higher swelling and appropriate mechanical properties of hemostatic samples synthesized at 15 kGy irradiation dose, this dose was selected for product synthesis. Fortunately, the absorption rate and capacity of hemostatic powder synthesized by irradiation method was higher than commercial samples.
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